Mayo Clinic in Rochester, Minnesota announces new postdoctoral positions in cancer genetics/cancer genetic epidemiology. Positions will be funded by the Mayo Cancer Genetic Epidemiology Training Program, which is supported by a grant from the National Cancer Institute, and are 3 years in duration. Mentoring will be provided by experienced faculty, including cancer genetic epidemiologists, statistical geneticists, cancer geneticists, bioinformaticians and clinical mentors. The goal of this traini...

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A post-doctoral research position in B-cell malignancy and high throughput RNAi screening is available immediately at the Mayo Clinic Arizona Cancer Center. Genome wide RNAi screens of myeloma cells in the presence or absence of chemotherapies have revealed multiple vulnerabilities in myeloma cells. Follow up studies of these RNAi identified hits are required. Excellent writing skills are mandatory. Experience with bio-analysis of large genome based data sets, familiarity with molecular biol...

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Postdoctoral positions are available to study regulation of genome stability by histone modifying enzymes in yeast and/or epigenetic silencing of tumor suppressor genes in mammalian cells. Please visit (http://ndc.mayo.edu/mayo/research/zhang_lab/) for current projects in the lab. Candidates who have solid background in molecular biology and biochemistry and are highly self-motivated in research are encouraged to apply. Experiences with mammalian cells or yeast are very important for the postdoc...

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POSTDOC POSITION NEXT-GENERATION SEQUENCING DATA ANALYSIS Mayo Clinic in Rochester, Minnesota is seeking postdoc candidates in methodology development and annotation of DNA sequence data from high throughput, next-generation sequencing machines (e.g. Roche/454, Illumina/Solexa, ABI SOLiD). Applicants must hold a Ph.D. degree in Bioinformatics, or related fields, having a solid background in developing bioinformatics tools, and with enough knowledge of molecular genetics. Experience with a...

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The division of Biomedical Statistics and Informatics is recruiting a bioinformatics postdoctoral fellow. The successful individual will join the bioinformatics team to work on the analysis of multiple large genomics data sets. The fellow will join the BORA development team (Biologically Oriented Repository Architecture) to apply and develop system biology methods to large datasets made up of several data types such as clinical data, gene expression, genotypes, resequencing data, microRNA expres...

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A postdoctoral research position is available immediately in cardiovascular bioenergetics, metabolomics and metabolic signaling area. A Ph.D. in biological sciences and a strong background and interest in biochemistry, cell bioenergetics and metabolic signaling are required. Familiarity with HPLC, GC/LC/MS, NMR, metabolic labeling and computational methods is a plus. ...

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A postdoctoral fellow position is available to study the molecular mechanism of aging and cancer. We are interested in the DNA damage response pathway, which is important for maintaining genomic stability and tumor suppression (Nature 421:957-961, 2003; Nature Structure and Molecular Biology, 12:589-563, 2005; Molecular Cell, 21:201-14. 2006). In addition, we are interested in the regulation of protein deaetylase SirT1 and its implication in aging and cancer (Nature, 451: 583-6, 2008). Applic...

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Research Associate In this position a self-directed researcher will design and implement translational research studies in Hematology, relating to B-Cell Malignancies, dissecting POEMS and Castleman?s disease. The researcher will determine the experiment progression, and analyze the results, as well as write manuscripts for publication and presentation at national and international meetings. Requires Ph.D. in Biology or related field; 3 years post-doctoral experience in Molecular and Cell ...

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Postdoctoral position available immediately to study induced pluripotent stem (iPS) cells for clinical interventions. Dr Ikeda's laboratory has special interests in iPS-mediated gene and cell therapy for type 1 diabetes and hemophilia. Applicant should have experience with cell culture and animal experimentation and preferably have some experience with viral vector techniques or stem cells. Candidate should also possess strong communication and writing skills. ...

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A postdoctoral position (NIH-funded) is available in the Department of Molecular Medicine, for a highly motivated scientist wishing to study the control of innate immunity and apoptosis by measles virus P, V and C proteins. The ideal candidate should have a recent doctoral degree with demonstrated experience in virology and immunology or cell signaling. References: Devaux et al., 2007, Virology 360:72-83, doi:10.1016/j.virol.2006.09.049 - Devaux et al., 2008,. J. Virol. 82:5359-...

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A recent Ph.D. in toxicology, pharmacology, or biochemistry is sought for a new 2-year research grant in collaboration with other investigators at Mayo Clinic and University of Minnesota. The aim is to develop compounds that target insect pests and disease vectors by reacting with a unique amino acid residue in invertebrate acetylcholinesterase (AChE). Work to date has identified molecules that irreversibly inhibit mosquito and aphid AChE in vitro without detectable effects on the human enzyme....

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A postdoctoral Research Fellow is sought by a Pharmacogenomics laboratory for a position that is available as soon as possible. This laboratory will focus on the pharmacogenomics of drug targets, especially those anti-neoplastic agents. Studies conducted include the use of high throughput genotyping and expression microarrays that might influence drug response, functional genomic, in depth mechanistic studies of the functional effects of DNA sequence variation and translational studies of the ...

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A 1-year training/fellowship (the Kurtz Fellowship), renewable for year 2, is available for 2009 for a highly-motivated trainee or fellow wishing to study the biology and/or treatment of multiple myeloma. The candidate will joint a comprehensive, world-leading multiple myeloma program at Mayo Clinic which offers a broad range of opportunities for clinical and laboratory-based research. The candidate should hold an M.D. degree and should have a strong commitment to pursuing a career as an academi...

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Mayo Clinic in Rochester, MN is seeking candidates for NIH-funded Clinical Pharmacology Fellowship positions. These positions are open to US citizens or permanent residents with M.D., M.D.-Ph.D., DO or equivalent degrees - especially those who have already completed residency training and who wish fellowship research training in clinical pharmacology, with an emphasis on the application of pharmacogenomics, pharmacometabolomics and molecular techniques to clinical pharmacology and related field...

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Applications are sought for a postdoctoral fellow to participate in a study of urinary proteomics in relationship to kidney stone disease. Protocols will be developed and implemented to identify novel inhibitors of urinary crystallization and stone formation....

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The Mayo Clinic College of Medicine Demyelinating Disorders Research Group has openings for Postdoctoral Fellows. This is a dynamic and well-funded, multi-investigator group conducting basic and clinical research in neurology with a focus on multiple sclerosis, Alzheimer's disease, Parkinson's, amyotrophic lateral sclerosis and stroke. The broad context of scientific interest is elucidating the role of immune function in the etiology and repair of CNS diseases. Mayo Clinic is a worldwide reco...

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A postdoctoral position in X-ray crystallography is available immediately to study protein complexes involved in DNA repair and cell cycle checkpoint signaling. Candidates should have a doctoral degree with demonstrated experience in macromolecular crystallography and protein biochemistry. http://mayoresearch.mayo.edu/mayo/research/staff/mer_g.cfm...

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A postdoctoral position is available immediately to study neurobiology of alcoholism and drug addiction, funded by NIH and the SC Johnson Foundation at Mayo Clinic College of Medicine. Our laboratory focuses on the integrated neural system of addictive behaviors in state-of-the-art facilities. The individual will have the opportunity to work with genetically engineered rodent models (e.g. Nature Neurosci. 7, 855-86, 2004; PNAS 21, 8215-8220, 2006; Genes, Brain and Behav, 6, 776-783, 2007). Quali...

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A postdoctoral position is available to investigate how disruption of cell division contributes to cancer. Candidates should have a strong background in molecular biology and cellular biology and experience with mouse models....

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A post doctoral fellowship is available for qualified individuals with a chemistry/bioinformatics background in the Mayo Proteomics Research Center. This fellow will work in a team environment with two dedicated programmers and staff scientists to help build new software and bioinformatics solutions for proteomics and metabolomics experiments and integrated tools for interpreting mass spectrometry data of proteins. The ideal candidate will bring a skill set that can be applied to increasing th...

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We are seeking a highly motivated postdoctoral fellow to study cell cycle control and genome instability in cancer. We are particularly interested in ubiquitin-mediated pathways (Genes & Dev. 21, 184-194; Mol. Cell 23, 589-596) and current projects include studying deubiquitinase involved in cell proliferation....

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A postdoctoral position is available immediately as part of a project that integrates X-ray crystallography and biochemistry to study protein complexes involved in cell cycle checkpoint signaling and DNA repair. The ideal candidate should have a recent doctoral degree with demonstrated experience in macromolecular crystallography and protein biochemistry. Applicants should be highly motivated. http://mayoresearch.mayo.edu/mayo/research/staff/mer_g.cfm...

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The applicant should be a postdoctoral fellow with basic animal and laboratory skills. He/She should be able to perform PCR for genotyping, immunohisto/cytochemistry, protein analysis, Western and Northern analysis. ...

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A postdoctoral position is available in a dynamic and enthusiastic environment in the Department of Ophthalmology, Mayo Clinic, Rochester, MN. The research focus of the laboratory is in understanding the cell and molecular aspects of glaucoma. Glaucoma is an eye disease that affects 70 million people worldwide. One of the main risk factors for glaucoma is high intraocular pressure. The tissue involved in the maintenance of intraocular pressure is the trabecular meshwork, a filter-like tissue mad...

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We are seeking a post doctoral person with good chemistry skills to work on serum biomarker method development and validation for Prostate Cancer. The project involves chromatographic fractionation of blood using various extraction systems and/or affinity columns. Quantitation of trypsin digested fragments is by API 5000 tandem mass-spectrometry(MS/MS)....

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A Postdoctoral Fellow/Research Associate position is avaiable in cardiovascular ion channel physiology. The focus of our research is on the regulation of ion channels in heart and blood vessels in diabetes. We perform whole-cell and single channel recordings in isolated cardiac and vascular myocytes and in cultured cells expressing wild-type and mutant channels. We also create transgenic models to study the molecular mechanisms through which reactive oxygen species modulate ion channels in diabe...

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