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Diana Gil Pages, Ph.D.

Photo of Diana Gil Pages ., Ph.D.
Diana Gil Pages, Ph.D.
email
Location: Minnesota
  • Primary Appointment
  • Immunology
  • Academic Rank
  • Assistant Professor of Immunology

Summary

T cell activation by the TCR/CD3 complex. The TCR/CD3 complex is a multi-protein membrane receptor that enables T cells to identify antigens. When antigen binds to the TCR, a conformational change is induced within the CD3 subunits (CD3Dc). Though important for optimal T cell activation, CD3Dc impacts signal transduction by unknown mechanisms. In my laboratory, biochemical and genetic approaches are used to study the molecular pathways downstream of CD3Dc related with signaling transduction. Additionally, in vitro and in vivo experimentation is designed to understand CD3Dc function in T cell development and T cell activation during immune responses.

Recent publications

See my publications

Education

Post Doctoral Fellowship – Professor Ed Palmer’s Group
Laboratory of Transplantation Immunology and Nephrology, Department of Research, University Hospital, Basel, Switzerland

Post Doctoral Fellowship – Laboratory of Dr. Balbino Alarcon
Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Spain

Predoctoral Fellowship – Laboratory of Dr. Balbino Alarcon
Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Spain

B.S. – Biologic Science
Universidad Autonoma de Madrid, Spain

Ph.D. – Biochemistry and Molecular Biology
Universidad Autonoma de Madrid, Spain


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